Protein Info for Shew_3589 in Shewanella loihica PV-4

Annotation: LysR family transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 PF00126: HTH_1" amino acids 11 to 69 (59 residues), 63.2 bits, see alignment E=1.8e-21 PF03466: LysR_substrate" amino acids 97 to 309 (213 residues), 65.5 bits, see alignment E=4.6e-22

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_3589)

Predicted SEED Role

"Transcriptional regulator VC0068, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QJ07 at UniProt or InterPro

Protein Sequence (330 amino acids)

>Shew_3589 LysR family transcriptional regulator (RefSeq) (Shewanella loihica PV-4)
MNLDNLARIDLNLLVMLQVLLEERSVTRAASRLHLSQSALSKSLNRLRDTLGDPLFIRTA
HGLKPTAHAALLGQQLPDMLQGLYQLTQPPSFNPASSRRQFSFAMVESAYETLIPYFIGP
LLNNAPNLRLDSYLWTEKSLSSLQKGQIDFGITGRDINPQSDLIIDRLPEGIAHQTLFTD
HQVCLVRQGHPMLPAIRNHQWDLDIYLEMSHVQVRCEGNEWWALDYFLAKSGQRRHLSTT
VPDFYGAASVCAHSDLIFTLPSSFAAHARKLYALEELPLPFDFHSLAYVLLWHERNDDEP
GHKWIRETICKRVAQAVNQPEDALSASGSA