Protein Info for Shew_3485 in Shewanella loihica PV-4

Annotation: peptidase S9 prolyl oligopeptidase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 654 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF20434: BD-FAE" amino acids 420 to 611 (192 residues), 38.1 bits, see alignment E=4.4e-13 PF01738: DLH" amino acids 441 to 640 (200 residues), 36.5 bits, see alignment E=1.4e-12 PF00326: Peptidase_S9" amino acids 443 to 653 (211 residues), 167.6 bits, see alignment E=1e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_3485)

Predicted SEED Role

"Peptidase S9, prolyl oligopeptidase active site domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QIQ3 at UniProt or InterPro

Protein Sequence (654 amino acids)

>Shew_3485 peptidase S9 prolyl oligopeptidase (RefSeq) (Shewanella loihica PV-4)
MKLIQSFSLACLCLISSQVTASNKDITELFSRSAEFSNVQISPDGDYLSAITSHEGKHML
MILDAKTKKPTNVVRFPDNAQVGQYVWVNNERVVLAKEYLKGWSDHPIYYGELMAVNADG
SKPTYLFGYKGGEQQTGSRIKKNTAIQATAYILDPMPEDDRYMLIQALPWGSGSANTVEN
LQQVYRVDVYKGTRRKIATSPISYARFLPDHDGEVRFVSGTRDYVSSQLYYRKDDEWVDT
DKLNLNLDDITPIAFGDDENSVYVLGSENGKPKGVYLVDIKSGKKQLISQDKVVDPSNVW
INRVNKQLYAVEYENGYPTYEFVDNDEKLATTLKQLLTALPGHQVHLVSQTNDMSKLIIK
AFNDRNPGDYYIFDATSKKLEYLVSQKKWLDPDKMAEMKPISFTARDGRVISGYLTLPYG
KEAKNLPLVVNPHGGPHGPRDWWGFDDQNQLIASQGAAVLQVNFRGSGGYGKEFEHAGHQ
KWGTEIQYDIIDATKYVIEKGFVDKERICIVGGSFGGYSALQSPILAPDLFKCAIGFAGV
YDLELMFNEGDVQGRRAGERYLKQVLGENEAMLEQMSPSKNVDKLKVNLLLVHGGEDERA
PIEQLEALEEGLKKHNYPYEKLVMDDEGHGFYNDEHRAKYYRQMMSFLKDNLKL