Protein Info for Shew_3370 in Shewanella loihica PV-4

Annotation: ribonuclease activity regulator protein RraA (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 161 TIGR02998: regulator of ribonuclease activity A" amino acids 1 to 161 (161 residues), 277 bits, see alignment E=5.4e-87 TIGR01935: RraA family" amino acids 5 to 154 (150 residues), 211.8 bits, see alignment E=4.2e-67 PF03737: RraA-like" amino acids 5 to 152 (148 residues), 136.2 bits, see alignment E=5.4e-44

Best Hits

Swiss-Prot: 89% identical to RRAA_SHEDO: Regulator of ribonuclease activity A (rraA) from Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)

KEGG orthology group: K02553, regulator of ribonuclease activity A (inferred from 100% identity to slo:Shew_3370)

Predicted SEED Role

"Ribonuclease E inhibitor RraA" in subsystem RNA processing and degradation, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QID8 at UniProt or InterPro

Protein Sequence (161 amino acids)

>Shew_3370 ribonuclease activity regulator protein RraA (RefSeq) (Shewanella loihica PV-4)
MEYNTSELCDTYIDVVDVVEPMFSNYGGCSSFGGSISTIKCFEDNGLIAEVLQQDGEGKV
LLVDGGGSLRRALVDANIAEIAVANNWEGIIVYGSVRDVDALEDLDIGIQALASIPVGAD
GHGVGELEIPVNFGGVTFLPADHIYADNTGIILSPEPLDID