Protein Info for Shew_3215 in Shewanella loihica PV-4

Annotation: ATPase, P-type (transporting), HAD superfamily, subfamily IC (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 868 transmembrane" amino acids 42 to 76 (35 residues), see Phobius details amino acids 209 to 231 (23 residues), see Phobius details amino acids 238 to 264 (27 residues), see Phobius details amino acids 653 to 675 (23 residues), see Phobius details amino acids 730 to 752 (23 residues), see Phobius details amino acids 789 to 809 (21 residues), see Phobius details amino acids 821 to 842 (22 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 5 to 52 (48 residues), 48.3 bits, see alignment 1.8e-16 TIGR01494: HAD ATPase, P-type, family IC" amino acids 65 to 313 (249 residues), 161.3 bits, see alignment E=1.4e-51 amino acids 564 to 682 (119 residues), 103.5 bits, see alignment E=4.8e-34 PF00122: E1-E2_ATPase" amino acids 93 to 271 (179 residues), 161.1 bits, see alignment E=6.2e-51 PF13246: Cation_ATPase" amino acids 356 to 443 (88 residues), 27.2 bits, see alignment E=9.3e-10 PF00702: Hydrolase" amino acids 412 to 607 (196 residues), 53.3 bits, see alignment E=1.5e-17 PF00689: Cation_ATPase_C" amino acids 677 to 849 (173 residues), 145.3 bits, see alignment E=5.3e-46

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_3215)

Predicted SEED Role

"Cation-transporting ATPase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHY3 at UniProt or InterPro

Protein Sequence (868 amino acids)

>Shew_3215 ATPase, P-type (transporting), HAD superfamily, subfamily IC (RefSeq) (Shewanella loihica PV-4)
MAVPGLSRQAAAERLEQYGPNCLPKPARLSFIRLFILQFKSAFIYVLLAAFIACLLLGQI
LNAIFIFAVLMLNAIIGTVQEYSAQQAADALSKMVPSQTKVIRDGHPKMVDSLSLVPGDY
ILLSNGDRIGADIKIEKHNQFKVDESALTGESVAVNKTDLAFAGTLVTHGRAEGEVIATG
ARTQIGQIADLVRQGGSAKPPLMQRIERFTLIIAIATLIIIALIFGLTLLRGADLSQVFL
LGVALAVSAIPEGLPAAITVALAIGMKRMSQANVIVRKLVAVESLGSCTYIASDKTGTLT
VNEMTISQISLLSGERYHVAGTGLTPTGLVHKHGHGVPVSTARDPELHRLALTGVLANEA
HLSFEAKQSHGDQMHADGDGVDLAFLALGYKLNLEMDKAKQPPQEQLFAYESENQFSASI
NQIEGRSVISVKGAVEKLLTMCQLDAQQTQAVLDETHWLARHGYRVLALASGEVSDPHHP
LADLDFLGLVAMSDPLREDAIEAVALCQQAQIKVAMITGDHPVTALALARQLKLANDQDG
VITGEQLTQVQQQSLAEFDHLIASHRVFARVQPRQKMEITESLIRQGEFVAMTGDGVNDA
PALKHAHVGIAMGLKGTDVARESADLVLTDDRFSSIVKGIIEGRIVYNNIRKVIYLLIST
GAAELLLFILSVLFAQPIPLFPLQILWLNLVTNGVQDVALAFEPGEGHEIDQPPRRPSEP
IFDRLMLERLIVSALWMGIVAFGLFSLVLAIGSSENDARNLTLMLMVLFENVHALNSRSE
RNSLLRMPVLSNPLLLFGIILAQGIHIGASYTPGLSQALGISPIGLGQWLMLLSAASTLL
FIDEYHKRLWRQQHKPKVRQATADRQLE