Protein Info for Shew_3124 in Shewanella loihica PV-4

Annotation: ATP-dependent helicase HrpB (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 843 TIGR01970: ATP-dependent helicase HrpB" amino acids 15 to 837 (823 residues), 1035.2 bits, see alignment E=0 PF00270: DEAD" amino acids 27 to 171 (145 residues), 46.4 bits, see alignment E=5.6e-16 PF00271: Helicase_C" amino acids 214 to 340 (127 residues), 46.9 bits, see alignment E=4.4e-16 PF08482: HrpB_C" amino acids 693 to 825 (133 residues), 159.7 bits, see alignment E=7.3e-51

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 100% identity to slo:Shew_3124)

Predicted SEED Role

"ATP-dependent helicase HrpB"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHP2 at UniProt or InterPro

Protein Sequence (843 amino acids)

>Shew_3124 ATP-dependent helicase HrpB (RefSeq) (Shewanella loihica PV-4)
MRPLNQVATQEFNQVPIQTLLPEIQRTLADNAQLILQAPTGAGKSTALPLAMLDWPEIEG
KILMLEPRRIAARSVAHFIAARRGEPVGQSVGFRVRGESSVSAKTRLEVVTEGVLTRMIQ
QDPELSGYGLIIFDEIHERHLTTDLGLALALEVQASFREDLKILAMSATLDGLPLQALMP
DAASLVSEGRSFPVSLSYRPSPAHQDWLLHMAKVIVEAVAEHQEGSLLAFLPGQREIARL
QMLLSERLDPKQFLITPLYGALPPSQQDSAIAPPPPGMRKLVLSTNVAESSLTIQDIRLV
VDAGYKRQASFNPKTAVSRLSLKRISQSSAAQRSGRAGRLSEGHCIRLWPQQEHERLLKA
DEPEILHGDLTNAVLDAAFWGVNTLDALPLISPPSEANETVASDLLQALALVDSDRRITA
HGRAAYRLGCHPRLAHMLLAAKELDGIDAPYYLPLAAVLAALLESRALARRGADISRYLN
DARGGEVAKLAQQYLARMNAARGNQIAKAIGESRDQDIATLLALAFPDRIAKARGAKGYQ
LACGAGVALNDDDALQGEPWLVVADFQESEGQSSGRILLAAKLDAALFDGPLASQVKSVV
ETGWDEEKARFYGLTQRRIGAIILGERPLATLDEETIKQAIYQLIRTKGLSLLGFDDKVE
QLRLRVALASKLALAGDWPDLSDQALLATLPEWLGPYLDGVRRLNQLKGLDFYTLLHNQM
EWGQQQILNEALPSHWPMKTGTRAAIRYEMSGRALLSVRLQEALGMAESPRLAQGQLVVT
MELLSPAMRPLALTADLANFWAGPYVEVKKEMKGRYPKHLWPDDPANTLPTKLTKKKMSA
KGL