Protein Info for Shew_3118 in Shewanella loihica PV-4

Updated annotation (from data): smc-like chromosome partitioning protein (DUF3584)
Rationale: Conserved phenotypes: important for motility and cisplatin resistance. DUF3584 is distantly related to smc proteins.
Original annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1223 transmembrane" amino acids 1118 to 1135 (18 residues), see Phobius details PF12128: DUF3584" amino acids 8 to 1195 (1188 residues), 1640.8 bits, see alignment E=0

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_3118)

Predicted SEED Role

"FIG020374: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHN6 at UniProt or InterPro

Protein Sequence (1223 amino acids)

>Shew_3118 smc-like chromosome partitioning protein (DUF3584) (Shewanella loihica PV-4)
MPSLNRIVLINTHLPGVVELALDGHTNICGTNASGKTTLQRLVPVFYGEYPSRVVPSTRD
SFERWYLPHDSSYIIYEYRRDDGLLTQAVLASAGDGKGVNYRFIGKGFELEDYVKSQQGE
SILCHNMAELGREMKRAGVAVTNLLNTREYRAIIQNDRTLLSTGSNRSELRAYARQFSLC
QHEHTLRHIEKLAKAVHSKEGKMETIKSMIAAILEEDGVNPPSSRLNPQRVEAWIRESQL
IQGFEQIRPEFDKLEQEFNQLLSAEQRLAGLKRGYGKDEAQEIERQELNQQRSKDLGNKL
RQLDDEWKELRDELNLDLSAAKGDVAKIEHELDIIEDQHAGFLDADIEQAKLDLEQLPSW
RASLENLTERHKLQTEKHQDIEAAYNARRSKIGENLNRELEQLDKEQDKHREARDKQQEV
GREELAALEQSWREQMEAGRAKHNEQEYQLKLTAAELQMQVNGVTYSEEEKLTLAVFDER
ISRADEEQEACNAMVDRLAGEERKLRAKRDQANESLRQAGLRVIERQGALDELHQVLFPQ
SHTLLEYLRKEVDGWEESIGKLINPELLHRSDLHPAKSAGGDSFCGVELDLKALTTPEYA
ASEQELRGRYSEAEEALANAKQLQAEAEEALVAINAELDKLNRELTFAKTAYKNSRDDLR
RLFDEKRAEQEKINQALSARKADSQKRLARLDSEMKQLKAQHQEWIDEQNEQALEARMEK
KAYWQEVVGALDVQLSQVKQNINDRRHAAKTEQKACEQWYKDELKSRGVDEAKIVKLKQE
IRDLESSISKAEQRRSEVLRFDDWYQHTWLARKPKLQTELSQVKMAVTELSQQLTTKANE
IKHQRQQYDSERKQSDAIQVEASENLTKLRAVMRKLAELKLPSSQDEMQGGLTERLRQGE
ELLLRRDQLMGSVKQYIEHFDSVIASKSGSSLSETWERAREESSFVNDKGIRLLDYRKLV
PQLEQLLNVMVPQAIMGLREQGRNFGIDLTAFYDVLADIDRRIASQSARITREVGEELFL
DGVSESAVRIRSRISELEFWPELEEFVKAFKQWKAEGFADLPDEHYTSSMRRALDIIGRA
ALTGGIAKLLEIELRLKEGNSDLVIRTDRQLNESSSHGMAYLILCKFLLAFTRLLRGRAD
VTIHWPIDELGTLHHGNVKKIFDACENNNISVLGAFPNPESEVLNLFANRYIINKQTKKL
QVVKPQVNPIADKLSQRFAKEAV