Protein Info for Shew_3080 in Shewanella loihica PV-4

Annotation: thiol:disulfide interchange protein, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 179 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details amino acids 23 to 23 (1 residues), see Phobius details transmembrane" amino acids 21 to 22 (2 residues), see Phobius details amino acids 24 to 24 (1 residues), see Phobius details amino acids 35 to 55 (21 residues), see Phobius details PF13899: Thioredoxin_7" amino acids 68 to 152 (85 residues), 45.5 bits, see alignment E=3.3e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_3080)

Predicted SEED Role

"Membrane protein, suppressor for copper-sensitivity ScsB" in subsystem Copper homeostasis: copper tolerance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHJ8 at UniProt or InterPro

Protein Sequence (179 amino acids)

>Shew_3080 thiol:disulfide interchange protein, putative (RefSeq) (Shewanella loihica PV-4)
MNNILLVSALTLSLLLGLFVWLSYKKLKGSQIPTGVLAVLLVFALINGAVSYFIAPKAGD
DAYKQLVWQSLSPNAIPDQLAQGKTVFVDVSADWCNICKANKDRVLHQAVVVERLKDKDM
VLMRGDLTQSDARIEAYLAQYQAYGVPFNIVYSQAHPDGLVLPRVLSIDDLLSALPPRD