Protein Info for Shew_2991 in Shewanella loihica PV-4

Annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 116 transmembrane" amino acids 23 to 40 (18 residues), see Phobius details amino acids 46 to 65 (20 residues), see Phobius details amino acids 77 to 97 (21 residues), see Phobius details PF05656: DUF805" amino acids 11 to 108 (98 residues), 100.5 bits, see alignment E=4.2e-33

Best Hits

Swiss-Prot: 46% identical to YHAI_ECOLI: Inner membrane protein YhaI (yhaI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2991)

Predicted SEED Role

"Integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHA9 at UniProt or InterPro

Protein Sequence (116 amino acids)

>Shew_2991 hypothetical protein (RefSeq) (Shewanella loihica PV-4)
MEYFIGALKKFADFTGRARRKEFWMFTLFYIIFYAVAATIDVVTGLYMLSGIFSLALLIP
TLAISARRLHDTGRSGWWQLIGLIPLIGAIVLIVFYVQDSVEGNEYGENPKALAEA