Protein Info for Shew_2989 in Shewanella loihica PV-4

Annotation: GDSL family lipase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF14606: Lipase_GDSL_3" amino acids 34 to 135 (102 residues), 27.9 bits, see alignment E=4.1e-10 PF00657: Lipase_GDSL" amino acids 35 to 127 (93 residues), 49.1 bits, see alignment E=1.3e-16 PF13472: Lipase_GDSL_2" amino acids 37 to 188 (152 residues), 90.9 bits, see alignment E=2.2e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2989)

Predicted SEED Role

"Acyl-CoA thioesterase I"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHA7 at UniProt or InterPro

Protein Sequence (203 amino acids)

>Shew_2989 GDSL family lipase (RefSeq) (Shewanella loihica PV-4)
MKLKWLLVPVILILAIIFWPSGGPSLAPLSGGARILAFGDSLTQGVGASPGMDYPAQLQA
MSGREVINAGISGETTSQGRERFARVLDETAPDLIILLEGGNDFLRNGNAAQVEANLSAM
LAQAQGRDIPVVLIGVPQKSIWLETAPLYGQLAAQYQPLFIEDFLTELLKLSEVKSDAIH
LNDEGYRRLAEHLYQSLQQAGAL