Protein Info for Shew_2936 in Shewanella loihica PV-4

Annotation: rod shape-determining protein RodA (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 368 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 50 to 68 (19 residues), see Phobius details amino acids 74 to 93 (20 residues), see Phobius details amino acids 115 to 132 (18 residues), see Phobius details amino acids 139 to 155 (17 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details amino acids 263 to 289 (27 residues), see Phobius details amino acids 305 to 329 (25 residues), see Phobius details amino acids 338 to 359 (22 residues), see Phobius details TIGR02210: rod shape-determining protein RodA" amino acids 17 to 364 (348 residues), 458.5 bits, see alignment E=8.2e-142 PF01098: FTSW_RODA_SPOVE" amino acids 23 to 364 (342 residues), 393.4 bits, see alignment E=4.6e-122

Best Hits

Swiss-Prot: 60% identical to RODA_SHIFL: Peptidoglycan glycosyltransferase MrdB (mrdB) from Shigella flexneri

KEGG orthology group: K05837, rod shape determining protein RodA (inferred from 100% identity to slo:Shew_2936)

MetaCyc: 60% identical to peptidoglycan glycosyltransferase MrdB (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Rod shape-determining protein RodA" in subsystem Bacterial Cytoskeleton or Peptidoglycan Biosynthesis

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QH54 at UniProt or InterPro

Protein Sequence (368 amino acids)

>Shew_2936 rod shape-determining protein RodA (RefSeq) (Shewanella loihica PV-4)
MNAHSHRPNIWQRMHIDLPLLLGLLALMCYGLFVIYSAGGEDMALMERQLIRMGLSLGIM
LFVAQINPEVLRRWAFPIYIAGVILLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAF
PITMAWYISKFPLPPKKRYLAGAGVILLIPTLLIAKQPDLGTSILVAASGIFVLFLSGMS
WAIVGSFIGGVLAMLPVLWFFLMHDYQRTRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGI
WGKGWLDGTQSQLEFLPERHTDFIFAVIGEEFGLIGSLILLCLYLYVIGRGLVIASRAQT
SFARLLAGSITLTFFVYVFVNIGMVSGLLPVVGVPLPLISYGGTSMLTLMTGFGILMSIH
THRRFIDR