Protein Info for Shew_2802 in Shewanella loihica PV-4

Annotation: periplasmic sensory protein associated with the TorRS two-component regulatory system (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF00532: Peripla_BP_1" amino acids 70 to 350 (281 residues), 49.1 bits, see alignment E=5.9e-17 TIGR02955: TMAO reductase system periplasmic protein TorT" amino acids 71 to 378 (308 residues), 354.1 bits, see alignment E=3e-110 PF13407: Peripla_BP_4" amino acids 76 to 340 (265 residues), 57.4 bits, see alignment E=1.7e-19

Best Hits

KEGG orthology group: K11930, periplasmic protein TorT (inferred from 100% identity to slo:Shew_2802)

Predicted SEED Role

"Periplasmic protein torT precursor" in subsystem trimethylamine N-oxide (TMAO) reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QGS0 at UniProt or InterPro

Protein Sequence (387 amino acids)

>Shew_2802 periplasmic sensory protein associated with the TorRS two-component regulatory system (RefSeq) (Shewanella loihica PV-4)
MVKHNKSPFFRAFSLCACLHGLAIAAGFSISVTANAVETWSLEQRTPYNAKLQQVKTLSY
RPLSTAKRPWRLCALVPHLKDAYWIGIDYGLVTRAQTLGVALELFEAGSYYGKAKQLEQL
EHCMKSDFDAILLGTVDPELLKQYQGQISKPMLALVNRLDSPLVSTRIGVNWYQMGWHAG
DFIHRTTAKQPGKANTEQANTDQTNTGQAVQLALLLGPEKLGGSTWVEQGIMEALEGSNV
SISSNRHADNNRDLYRDQLHHLLKDHRPDYILGSAVAIEAAIGALAQKDTAQDIALVSSY
LSPATLRGLYRHRVAFSSDDQVVLQGKLAIDVVVRELEGAAPFGDIGPRIKGLTPDNIQM
KQLTDSLAPADFYPIYRVEAPKATPQP