Protein Info for Shew_2752 in Shewanella loihica PV-4

Annotation: peptidase M61 domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 598 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF17899: Peptidase_M61_N" amino acids 24 to 187 (164 residues), 158.9 bits, see alignment E=2.4e-50 PF05299: Peptidase_M61" amino acids 277 to 390 (114 residues), 127.7 bits, see alignment E=6.4e-41 PF13180: PDZ_2" amino acids 485 to 556 (72 residues), 33.8 bits, see alignment E=7e-12 PF17820: PDZ_6" amino acids 496 to 521 (26 residues), 28 bits, see alignment (E = 3.2e-10)

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2752)

Predicted SEED Role

"Aminopeptidase N family protein, contains PDZ domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QGM0 at UniProt or InterPro

Protein Sequence (598 amino acids)

>Shew_2752 peptidase M61 domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MKLAVPLILIFSPFFLSQAHADVNYRIDLTQPQHHLAKVEVDFPRSEAKQLSVNLPVWRT
GKYQVLPLGDAIRHFRAEDESGRALAWQRSASGEWQVKLSQPTQVKVTYQLYANSLGQRV
SHIDASHAYLDASGVFVYSPDFRDQKVNVSLKVPEAWRSYSGMESKDAHLFIADNYDVLV
DSPIETGISQHRAFSADGRDYELVVWGEGNYDLDKMVEDLTKLSGQAKAIWSGYPFKRYV
YMVHATSGASGATEHLNSTVIQRPRFSFRERKDYLGFIKTASHEFIHTWNVKAYRPQGLV
PYDYQQEGITELLWIAEGSTSYFQSQLLLRAGVITPKEFLEDLARRITRNEQTPGREVQS
VAEASAGQWVAGGGDYAQNHSSNIYAEGYLTSLALDFSLLSDTRLKTSYRDLHAKLYQDF
KLPVGYQVSDVQQILRELSGKDYGDWWQRHVNSPLVLDYEALLAKAGLKKDYGSDNKAIA
YAGMQTREGSLRLSHVKREGPAWRAGIVAGDELVAINGLKVTAEGFAARIKDFTPGDTIK
VTLFSNDTLKEVALTLAEQPSEKLKLVSVDKPSRKQKAFFKAWLGIDWPFDGEGKLKK