Protein Info for Shew_2708 in Shewanella loihica PV-4

Annotation: Na(+)-translocating NADH-quinone reductase subunit B (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 transmembrane" amino acids 52 to 72 (21 residues), see Phobius details amino acids 112 to 135 (24 residues), see Phobius details amino acids 147 to 176 (30 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 253 to 278 (26 residues), see Phobius details amino acids 286 to 305 (20 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 347 to 365 (19 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details TIGR01937: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit" amino acids 19 to 398 (380 residues), 443 bits, see alignment E=5.2e-137 PF03116: NQR2_RnfD_RnfE" amino acids 37 to 395 (359 residues), 317 bits, see alignment E=7e-99

Best Hits

Swiss-Prot: 55% identical to NQRB_PSEA6: Na(+)-translocating NADH-quinone reductase subunit B (nqrB) from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)

KEGG orthology group: K00347, Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC: 1.6.5.-] (inferred from 100% identity to slo:Shew_2708)

Predicted SEED Role

"Na(+)-translocating NADH-quinone reductase subunit B (EC 1.6.5.-)" in subsystem Na(+)-translocating NADH-quinone oxidoreductase and rnf-like group of electron transport complexes (EC 1.6.5.-)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.-

Use Curated BLAST to search for 1.6.5.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QGH6 at UniProt or InterPro

Protein Sequence (404 amino acids)

>Shew_2708 Na(+)-translocating NADH-quinone reductase subunit B (RefSeq) (Shewanella loihica PV-4)
MSKQDNKPDVQENYYAHGSSMRSFLRSLLYAHGRSTKGKVHVRDAIDVKRTMTLVGLCLL
PAILFGIYNLGLQAQLALASGLTTPDVWQLLPFNAITGGLGEQSGFFGLFGYGLSFYLPI
YLTALLVSLFWEMVFAKVRRQELHEGFFVTALLFTLILPVSTPLWIVALGITFGVIMAKE
VFGGMGYNFLNPALAGYAFIYFAYPTEVAQIAQFVAVDGFSGATTLIQTAAGKMSFEGYT
WYQAFSDPLWWDAFFGFTVGSIAETSTLAILIGGLLLLLTRLADWRVVAGVMAGMVATAV
LFNLIGSAKNEMFAMPWTWHLVTGGFALGMMFMATDPVTTAYTRQGKFAYGVLIGFMTVL
IRVLNLKMPEGIMLAILFANLWAPLFDYLVARSNMKRRLKRNAL