Protein Info for Shew_2690 in Shewanella loihica PV-4

Annotation: TonB-dependent receptor, plug (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 812 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF07715: Plug" amino acids 62 to 163 (102 residues), 77 bits, see alignment E=1.6e-25 PF00593: TonB_dep_Rec" amino acids 304 to 782 (479 residues), 93 bits, see alignment E=4e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2690)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QGF8 at UniProt or InterPro

Protein Sequence (812 amino acids)

>Shew_2690 TonB-dependent receptor, plug (RefSeq) (Shewanella loihica PV-4)
MKQMRLSAVALGCAVSLSVSAEQHNTSIEQQASAEVERITVYGRQNKVVMNSGLATKSDM
SLMETPAAVVVVDEELITTQGATELQELLRNISGVTQAGNNYGIGDNIVIRGLGANYTYD
GMYGGAGLGNTFNPTRSLTNVESVEVLKGPATGLYGMGSAGGVINLIEKKPQFNASHQFT
AEVGQWDSYSLGLDSTAALTDKAAYRLVAKHARSEGYRDIGTDRDEAYASLKYLLSDQQD
IMLSAAYIKDAIAVDSIGHPIRIYNAASVGGKPAGEVSWQDLINDASNAGLQLSDEQRQQ
LADSLSAGDGLTPYAFGEAGIISPMAKDNEGEELRFKLTHNIFFADNLFLNQQLQYRDYQ
SGFARQTGAYNYVYWNRNGVINSDPRAPLVVDDRLYPFAARRQEYRQVQADETSWQYFAD
LRYDFSVAGIDNELLVNANFEDRNIRFKQYSIYDADKVIKNKAGEVIYQGQLPYIFDIRS
PNWAEGQFEDYDPLMTSNYNKKVQAWGVGLQHVGYFDFGITTRIGVAFNDISQRYEHYGV
DARYSASLAQPTPEADTSDDGMTYNLGITYMPTDDLSFFINHAKGRTAYSVLGSLKGDGA
DREDSESISNDIGVRFKAFDDQMLASIVVFESSRTNLQYNNKDYEAGVSGPDVAQYFYDG
KEETKGVELDLNAHLGERWAINVNGVYQDARDKQDPNSTSFDTRQKGVPYVTASTWVTYD
ADWFKLPSPLSVSLGAKYVDERSTHSASFGIPDGYVPSYTVMDAALSYQADSWTVQLNVN
NLLDEHYYEKAMFLGGMPGAERNAKLSLSYRL