Protein Info for Shew_2544 in Shewanella loihica PV-4

Annotation: phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 584 transmembrane" amino acids 130 to 146 (17 residues), see Phobius details PF02878: PGM_PMM_I" amino acids 45 to 181 (137 residues), 145.6 bits, see alignment E=1.6e-46 PF02879: PGM_PMM_II" amino acids 213 to 314 (102 residues), 79.6 bits, see alignment E=4.7e-26 PF02880: PGM_PMM_III" amino acids 334 to 455 (122 residues), 46.6 bits, see alignment E=6.8e-16 PF00408: PGM_PMM_IV" amino acids 525 to 550 (26 residues), 29 bits, see alignment (E = 1.8e-10)

Best Hits

KEGG orthology group: K01840, phosphomannomutase [EC: 5.4.2.8] (inferred from 100% identity to slo:Shew_2544)

Predicted SEED Role

"Phosphomannomutase (EC 5.4.2.8) clustering with Aga operon" (EC 5.4.2.8)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QG12 at UniProt or InterPro

Protein Sequence (584 amino acids)

>Shew_2544 phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq) (Shewanella loihica PV-4)
MQTQIQARIKHWLSLDSDAKSRAEIQALVDQGAQEELVARFAGRLTFGTAGIRGVVGAGP
MRMNRLVVQQTSKGVAEYLKAQVENAVSRGVVIGYDGRHDSKQFAEDAASVLTAAGFKVF
LTSKVAPTPLVAFGVLHLGAAAGIVVTASHNPPQYNGYKVYWGNGAQIIPPHDTGIAARI
ELAANSPVDMLPLETAVETGKLVMLEEDYYQAYRQGVLNAEVLQSPARPELVSLAYTAMH
GVGAEMAETLLKDIGVTQVYSVAAQREPDGDFPTVNFPNPEEAGAMVLVMAEAHKHGAML
ACANDPDADRFAVAVRKPAATPEMLASEAYQMLTGDQVGVLLGHYLLSHASDDQRLLCCT
IVSSSLLTRISEACGARCETTLTGFKWLTNVGMSKQTQENRFLFAYEEALGYTVGSMVWD
KDGLSALVAFVQLTAELAAKGETLWDRLETIYRQYGYYLNRQVSIALSGEPGAPTIGEQL
RALDPSEIAGRALVSVDDISLGVRRFADGREETIDLPRSDVLIYRLQGNARVIVRPSGTE
PKVKCYYEVVEPFGEQEGLADVQRRAEAAMAEFVSRHQAGLPNA