Protein Info for Shew_2483 in Shewanella loihica PV-4

Name: dinG
Annotation: ATP-dependent DNA helicase DinG (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 690 PF13307: Helicase_C_2" amino acids 530 to 684 (155 residues), 148.3 bits, see alignment E=2.3e-47

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 100% identity to slo:Shew_2483)

Predicted SEED Role

"ATP-dependent helicase DinG/Rad3" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QFV1 at UniProt or InterPro

Protein Sequence (690 amino acids)

>Shew_2483 ATP-dependent DNA helicase DinG (RefSeq) (Shewanella loihica PV-4)
MLSADVKTQIRTIYKEIAAALPNFRSRREQNYIVAEISKTLAGEYDKHRRIIVVEAGTGI
GKSLAYILGSIPLALASKKKVCIATATVALQEQLLNKDLPFFSKQSGLNFTFGLVKGRQR
YVCLSKLEMLIGGDDGTQMAMWQTKPDHNQVELLQGLLKDFHEGRWNGERDTLSQQLPDH
LWQQIACDKHSCHRQLASHRHCPFHKAREDVDTWDVLIANHSLLFADLELGGGVILPDPE
ELYYVIDEAHHLPIVARDFSSAQATLRGAIDWLEKVGKTSAKLQNQLKSYNIIAPAQAML
DHINDLTSLLTSVAQYCDGQAAKFDNPERRIRFEHGKLPAALTMLAENLATASSSALKQF
NKMLVLLNEAIKDGELPKHQSEQLLSETGFMLQRLENLQKLWKMMAKEDSAKGAPMARWV
EHLVGKQSDYLFNVSPIEVGYMLETLLWEKAAGVVLCSATLRALNNFNHFTHQVGLSIND
GSRYLAMDSPFDFQQNATLYLPKMRTEPTDDRYTDELAEQILTLIDGEMATLVLFASYWQ
MEKVADLVRSKIKSPLLIQGEASRQQLLQDHKQRCDNGEVSIIFGTGSFSEGLDLPGDYL
TNLIITKLPFAVPTSPVEQAHAEYIKAKGGNPFLQLTIPDASRKLIQSCGRLLRKEEDYG
RITILDRRLVTKRYGKSLLDALPPFRQVIE