Protein Info for Shew_2379 in Shewanella loihica PV-4

Annotation: chromosome segregation protein SMC (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1141 PF13175: AAA_15" amino acids 1 to 421 (421 residues), 42.3 bits, see alignment E=1.5e-14 TIGR02168: chromosome segregation protein SMC" amino acids 2 to 1131 (1130 residues), 993.4 bits, see alignment E=8.2e-303 PF02463: SMC_N" amino acids 3 to 1124 (1122 residues), 222 bits, see alignment E=1.3e-69 PF13476: AAA_23" amino acids 5 to 226 (222 residues), 37.9 bits, see alignment E=6e-13 PF13304: AAA_21" amino acids 26 to 172 (147 residues), 31.5 bits, see alignment E=4.1e-11

Best Hits

KEGG orthology group: K03529, chromosome segregation protein (inferred from 100% identity to slo:Shew_2379)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QFJ7 at UniProt or InterPro

Protein Sequence (1141 amino acids)

>Shew_2379 chromosome segregation protein SMC (RefSeq) (Shewanella loihica PV-4)
MRLTQIKLAGFKSFVDVTKIPFNQPLTAIIGPNGCGKSNVIDAVRWVLGESSAKHLRGDS
MADVIFNGSSARRPVSVASVELSFDNQQGRLGGQYASYQAIAVKRQVSRDGESSYFLNGQ
KCRRKDITDLFMGTGLGPRSYAIIEQGTISRLIESKPQELRVFIEEAAGISRYKERRRET
ENRIRHTRENLERLGDIRQELGRQIDKLAEQAEAARQYRALKQTERDQHAQLEVAKYLEL
SAQSDKLSQEIEAKTLTQSEGDAGREALSRNLTEIKLKLDELERQEQQQVEAFYLNGNQI
AKLEQEVKHRQQQDAHLKQRIKQDEEKLALLKAQEQALILARGDLDERQHGAREAHQALQ
LQLELLDEQLGEVELSLEQAQEAESQAKQAVNQCQLRLELTKGELKHKQSALAQVKSQHQ
SASRQLEQLSHQDETDNLALQHAQCERLAERLDELKGEIELGAATQSQRQEQARQTQAQV
EALSQSLAEERGRLAVVKRILPQEDALQGRALWQAIQVTPGWEAAVDLLLDGLLTQKVSD
KHSGMETENESGFELSRSQKWTGLSSEVNLAPWLSRLNWADSLSQAKAMLGSIEDDERIV
TADGYIVGNGFVLQKAEQGRQLVQLKAEQQALELSIAASVEAIDERRAVLAEVNQALDEQ
REALTQLNTSLQGTQLERERLMAQAQATQERIAQQGEQQARLKALLEEQIGELEAVEQSL
SELTSRRDQDEAQLTELTRSADSQVAGLADRRAQHKALGRERQALALQSQQLQQSLQAIN
TEQALSRQQGEQLERQMKELAQELSELQGQLEGQDKLDGKLQADAMAAQLNDALARQGEV
QAALDALRLQQAELQNQADEIGAKQKQQLGKLEHLTQAISALKLRREGIKGQIDSQLAQI
RSQEVDIAEVQATLDLTVSLSHRQKTLERTKAQIEHLGAINLAAIEEFEQQSQRKAYLDS
QDADLAKALGSLEEAIRKIDRETKTRFKETFDKVNQDLGVLFPKVFGGGSAYLALTDDDL
LETGVTIMARPPGKKNSTIHLLSGGEKALTALSLVFAIFRLNPAPFCMLDEVDAPLDDAN
VDRFCRLVKEMSQSVQFVYISHNKITMELADQLIGVTMHEPGVSRIVAVDIDEAVALADA
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