Protein Info for Shew_2372 in Shewanella loihica PV-4

Updated annotation (from data): small component of L-lactate and L-malate uptake system
Rationale: PFam PF13937.2 (DUF4212). conserved cofit with Shew_2371
Original annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 88 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 53 to 74 (22 residues), see Phobius details PF13937: DUF4212" amino acids 10 to 86 (77 residues), 118.9 bits, see alignment E=5e-39 TIGR03647: putative solute:sodium symporter small subunit" amino acids 12 to 87 (76 residues), 116.8 bits, see alignment E=2e-38

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2372)

Predicted SEED Role

"FIG152265: Sodium:solute symporter associated protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QFJ0 at UniProt or InterPro

Protein Sequence (88 amino acids)

>Shew_2372 small component of L-lactate and L-malate uptake system (Shewanella loihica PV-4)
MAFENNEKAEGYWRENLRLVLGLLAIWAAVSFGCGILLVDVLNEIHFMGFKLGFWFAQQG
AMYVFVALIFVYVAKANALDKKYNVHED