Protein Info for Shew_2210 in Shewanella loihica PV-4

Annotation: proprotein convertase, P (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 transmembrane" amino acids 29 to 47 (19 residues), see Phobius details PF01483: P_proprotein" amino acids 309 to 386 (78 residues), 60.5 bits, see alignment E=6.8e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2210)

Predicted SEED Role

"Serine protease, subtilase family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QF28 at UniProt or InterPro

Protein Sequence (403 amino acids)

>Shew_2210 proprotein convertase, P (RefSeq) (Shewanella loihica PV-4)
MKSNHSAAGLTYIQAGQTPEAQAVNNNRLSLFAILLLFMLTPFTHGSSEFRAHQSRYDDP
LLNMVAEDRETLEKFNAQSKATIGSVERKTKQIDSMSQAIKTNTKTGIPLASEHKKASAT
LGGEAAATSIAKRNKPTASTQGFMLSVKEQRLSRAAGETAIYHFSTLVDRTLEDKAPEDR
ALEQRALIDTSLTGTSLVSEKLGGQICLSLASSLPGARLSKERVHPGDTFSLLVPSNSDA
RWGDYMFTVTASADGGNWVKQQSVNLSLLPGDIREIQQANFTWHPITDNAPEGIVSRIAV
EDELAAFGVRVLVNVSHTWHRDLSMTLTSPTGTSYQLVSESHAGGDNQHREYRTQAFNHE
AIKGDWILKVSDLAAGDIGTLRGWQLLISGYSAAQPQDISASP