Protein Info for Shew_1931 in Shewanella loihica PV-4

Annotation: alkylphosphonate utilization operon protein PhnA (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 114 PF08274: Zn_Ribbon_YjdM" amino acids 4 to 33 (30 residues), 52.8 bits, see alignment E=3.1e-18 TIGR00686: putative alkylphosphonate utilization operon protein PhnA" amino acids 5 to 112 (108 residues), 153.3 bits, see alignment E=1.2e-49 PF03831: YjdM" amino acids 47 to 113 (67 residues), 98.6 bits, see alignment E=1.5e-32

Best Hits

Swiss-Prot: 62% identical to YJDM_SHIFL: Protein YjdM (yjdM) from Shigella flexneri

KEGG orthology group: K06193, phosphonoacetate hydrolase [EC: 3.11.1.2] (inferred from 100% identity to slo:Shew_1931)

Predicted SEED Role

"Alkylphosphonate utilization operon protein PhnA" in subsystem Alkylphosphonate utilization

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.11.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QE99 at UniProt or InterPro

Protein Sequence (114 amino acids)

>Shew_1931 alkylphosphonate utilization operon protein PhnA (RefSeq) (Shewanella loihica PV-4)
MSDTIPPCPKCESPYAYEDGSLLICPECAHEWNPNEVAVDPDAIILKDAVGNLLEEGDKV
TLIKDLKVKGTSLTLKVGTKAVINRFVDADHDIDCKVDGHGQMMLKSKFVKKQS