Protein Info for Shew_1835 in Shewanella loihica PV-4

Annotation: glutaredoxin-like protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 116 TIGR00365: monothiol glutaredoxin, Grx4 family" amino acids 7 to 103 (97 residues), 153.9 bits, see alignment E=5.4e-50 PF00462: Glutaredoxin" amino acids 19 to 83 (65 residues), 71.4 bits, see alignment E=3e-24

Best Hits

Swiss-Prot: 75% identical to GLRX4_ECOL6: Glutaredoxin 4 (grxD) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K07390, monothiol glutaredoxin (inferred from 100% identity to slo:Shew_1835)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QE03 at UniProt or InterPro

Protein Sequence (116 amino acids)

>Shew_1835 glutaredoxin-like protein (RefSeq) (Shewanella loihica PV-4)
MDTNETVEKIKQQIAENPIIVYMKGSPKLPSCGFSSQVAQIMINCGAQFAYVDILQHPDI
RAELPKYANWPTFPQLWVEGELIGGCDILTEMYQKGELQTLIADTAAKYADQEGEA