Protein Info for Shew_1801 in Shewanella loihica PV-4

Annotation: putative solute/DNA competence effector (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 PF04352: ProQ" amino acids 10 to 116 (107 residues), 137.6 bits, see alignment E=1.6e-44 PF17516: ProQ_C" amino acids 167 to 214 (48 residues), 71.9 bits, see alignment 2.2e-24

Best Hits

Swiss-Prot: 81% identical to PROQ_SHEPA: RNA chaperone ProQ (proQ) from Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)

KEGG orthology group: K03607, ProP effector (inferred from 100% identity to slo:Shew_1801)

Predicted SEED Role

"ProQ: influences osmotic activation of compatible solute ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QDW9 at UniProt or InterPro

Protein Sequence (215 amino acids)

>Shew_1801 putative solute/DNA competence effector (RefSeq) (Shewanella loihica PV-4)
MMESTEKLTDTNAILAYLYETFPLCFIAEGETKPLKIGLFQDLAERLADDSKVSKTQLRI
ALRRYTSSWRYLKGVKAGAQRVDLDGNECGELEQEHIDHAQATLKESQEKAKAKRAAKAA
AEKTDKSGPKPEKKAFKKPLPKRSSKPASKAAKPQVEAKDLSPATLTELKPNQRVSVKLG
KSPVAGVVLDIKKEDVQVQLDSGLTVKVPVEHILL