Protein Info for Shew_1779 in Shewanella loihica PV-4

Annotation: alkaline phosphatase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF23657: DUF7151" amino acids 42 to 89 (48 residues), 47.9 bits, see alignment 1.1e-16 PF22494: choice_anch_I" amino acids 115 to 554 (440 residues), 407.9 bits, see alignment E=6.6e-126

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1779)

Predicted SEED Role

"Alkaline phosphatase (EC 3.1.3.1)" in subsystem Phosphate metabolism (EC 3.1.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.1

Use Curated BLAST to search for 3.1.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QDU7 at UniProt or InterPro

Protein Sequence (627 amino acids)

>Shew_1779 alkaline phosphatase (RefSeq) (Shewanella loihica PV-4)
MNNKMKKTAIAVVMTTLGLTACSGDEGKDGANGSNGTNGASSLVAFTQLPAGDLECPLGG
QMIQTGLDLNGNGVLDSDEVNAEQTQYLCRETVSGLSAELVGRYESGVYGQSAAEIVGFH
VASKRIFVVNAQSGKVDIVDAANLAASPAAGSDALVLNNLPKLAVLDVAQDLALQRLGGV
NSLAINGDLLAVAIERGDEAGNSKQGMGYVAFYRIDSAGEASLIHGVEVGALPDNVVFSH
DGKQVLVAGEGEPSDDYSVDPLGTVAIIAVTDGIPATSATLLDFSDFNLGGAREAELSSD
IKINGPGASRAQDLEPEYISVSPDNKLAYVSLQENNAIAVIDIPSKAVKAIWPLGFKDFG
LGKNAIDASDKDDRVNIQAYPGVVGLYQPDTIASYQWHGSDFVVTANEGDSRDYGGFSEE
ARAGDLTLDANHPQFAAAQDKTQLARLKVTTSMGDEDGDGDFDKIVAYGGRSFSIWDQNG
QQVFDSGSDFSRITAALLGMNFNNNNEENKGDSRSDDKGAEPEALAIGEIEGKRYAFIGL
ERTSGFMIYEITNPFAVKFVDYVVNRDFEVGFEIDGSDITGSPEVAGDLGPEGMSFVAAA
DSPNGKPLLIIGNEVSGSTSVYQLSLQ