Protein Info for Shew_1550 in Shewanella loihica PV-4

Annotation: FAD linked oxidase domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1026 PF01565: FAD_binding_4" amino acids 52 to 192 (141 residues), 114.6 bits, see alignment E=4.4e-37 PF02913: FAD-oxidase_C" amino acids 284 to 540 (257 residues), 192.7 bits, see alignment E=1.4e-60 PF13183: Fer4_8" amino acids 577 to 681 (105 residues), 28.9 bits, see alignment E=2.1e-10

Best Hits

KEGG orthology group: K06911, (no description) (inferred from 59% identity to asa:ASA_2502)

Predicted SEED Role

"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.99.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QD69 at UniProt or InterPro

Protein Sequence (1026 amino acids)

>Shew_1550 FAD linked oxidase domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MLPKLSHQQTLEPVYLAFLDALAQSNYCGDIDKRYSARLAQATDNSVYQFLPQAVLYPKT
QADVKLIMTLATKPEFKQVVFSARGGGTGTNGQSLTHGLILDLSRYFNQVIEINEKERWV
RVQAGVVKDALNDALRPHGFFFSPDLSTSNRATMGGMINTDASGAGSLVYGKTSDHVLEL
ISVLYDGSVLETKPLDLKALEALDALESPSLGQSLQRDIARMTREHRGEVESRFPKLNRF
LTGYDLKNVWNETVDEFNLSRILTGSEGTLAVITEAKLDITPLPKTRMMVNIKYDSFQSA
LRHAPDLVKAEVTVVETVDSKVLNLAKQDIIWHSVSSLIEDVPGASIDGLNMVEFAGEPD
EVEAKVKQLEAMLDTQLAANEAGLLGYQVTSDKASINTIYAMRKKAVGLLGATKGSRKPI
AFAEDTAVPPEKLADFILEFRALLDSHELQYGMFGHVDAGVLHVRPALDMCDPQDERLLK
TVSDQVAALTLKYGGLMWGEHGKGVRGEYGPSVFGETLFGLLEEVKGYFDPNNKLNPGKL
VAPKGSGPLLYNVDSTKRGAFDRQIPVNTREAFPDVMNCNGNGLCFNYSVYSPMCPSFKV
TGDRVQSPKGRAGLMREWLRLLEAEGVDVEALAKAKPLGWLQRTQNTLKKEREYDYSHEV
MESLKGCLACKACSSQCPVKVDVPKFRAQFFNIYYQRYLRPVKDYLVAGIEESLPLMAKV
PQITNFASQNKLSQWVIKQSIGYVDAPALSVPTLKQRLENHACRGYDLNALQQIPEAERD
QYVLVVQDPFNSFYEAETVYHFIKLIEKLGFKPVLLPFKPNGKPIHIKGFLDKFAKTAQS
SADFLNQVHALGMPMVGVDPAMVLCYRDEYKEILAENRGDFNVLLANEWLLKVIDIVAPT
AKSAKLNKSANATNANRQFTWFSHCTESTAKPNTAKEWQAIFSAFGAELSTVSLGCCGMA
GTYGHESDNLKRSKALYEMSWEKAIDSLPHEQILISGYSCRSQVKRFGGFKPKHPVQALL
SLIDNV