Protein Info for Shew_1261 in Shewanella loihica PV-4

Annotation: type III restriction enzyme, res subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 861 PF04851: ResIII" amino acids 3 to 224 (222 residues), 46.2 bits, see alignment E=4.9e-16 PF27151: YagJ" amino acids 709 to 860 (152 residues), 201 bits, see alignment E=1e-63

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1261)

Predicted SEED Role

"FIG00640257: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QCD3 at UniProt or InterPro

Protein Sequence (861 amino acids)

>Shew_1261 type III restriction enzyme, res subunit (RefSeq) (Shewanella loihica PV-4)
MKFTLKDYQRDAVRDALNNLKDAQDDWRRKSRKCAFSLTAVTGAGKTVMAAAAFEALFHG
DDEFDFDADPGAVVIWFSDDPSLNEQTRFRLMEASDRINHTDLVVVENTFNRPRFEAGKI
YFLNTQKLGKNSLLVRGHNQEELEAQAGSLFPETRPDLRAYTIWDTIQNTIEDPELTLYL
VLDEAHRGMGNAAVKEKGTIVQRLINGFGSVPGIPVVWGISATVERFNKAIECAGKHIKL
PNVVVDADKVQESGLIKDTILLDIPDETGDFDTVLVRRATDKLKESTIAWQEYTKQQEEA
RVVVPMMVLQVPNTPDPNEIGRALDTIFDRYPELPATSVAHVFGDHTTQQFGNHNVPYIE
PQRVQDSTWVRVLIAKDAISTGWDCPRAEVMVSFRAASDRTHITQLLGRMVRSPLARRIP
GNDRLNAVDCLLPKFNRKTVEEVVDALMNGDDSAPPTGRILVDYVELKPHPKANKSVWDA
FEALPSQNRPQRGAKPAKRLTVLAHELASDGILAGAGRLAHGVLHKALDAFQESQKDKIQ
GKRKSVLTVDGKTVIADMKGKEKTFDEFWEDADVAVIDDAYRRAARIFSPDIAKTYVEHL
ARQVADLDDDPEEFLEAIVEARVTVAGLGLVTEVQAYFDAEADKLAKEWLVKYASQIKAL
SDDRKESYRQIVEMSTEPQSFDLVKPESRCEAAKARESDKEIKFPTWNNHLLSDKDGKYP
VEMNEWERTVVEAESKRDGFLFWYRNPQQPGQSSLGIAYLEDEQFKIVRPDFIFFAEQDD
KIVVDLVDPHGVHLADALPKLQGLAAYATKHANAYRRIEAVAEAHGKLRVLDLTRTDVRQ
AVLDASSAKSLFEGLSADDYV