Protein Info for Shew_1116 in Shewanella loihica PV-4

Updated annotation (from data): N-acetylglucosamine kinase (EC 2.7.1.59)
Rationale: Specifically important for: N-Acetyl-D-Glucosamine. The first step in NAG utilization (SEED_correct)
Original annotation: ATPase, BadF/BadG/BcrA/BcrD type (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01869: BcrAD_BadFG
  • amino acids 13 to 291 (279 residues), 116.1 bits, E=1.1e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1116)

Predicted SEED Role

"N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59)" in subsystem Chitin and N-acetylglucosamine utilization (EC 2.7.1.59)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• chitin derivatives degradation (3/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.59

Sequence Analysis Tools

See A3QBY9 at UniProt or InterPro

Protein Sequence (299 amino acids)

>Shew_1116 N-acetylglucosamine kinase (EC 2.7.1.59) (Shewanella loihica PV-4)
MGFNQTEEQALVIGIDGGGSKCRATIYAADDSVLGTGVAGRANPLYGLTHTFDSISRATE
LALQDAGLKAGDGKTMVAGVGLAGVNVAHLYQAIKAWQHPFAEMYVTTDLHTACIGAHKG
GDGAVIITGTGSCGYAHVGEQSLSLGGHGFALGDKGSGAWLGLQAAQQVLLDLDGFGPAT
QLTERLLEHFKVNDAMGIVEHLAGKSSGCYATLARTVLSCAQAQDEVAKAIVVEGAEYIS
ALAHKLFEIHPPRFSMIGGLAEPLAPWLDKRVVDKISPILAPPELGAAYFARQQLGFSS