Protein Info for Shew_1039 in Shewanella loihica PV-4

Annotation: phosphoenolpyruvate-protein phosphotransferase PtsP (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 743 PF13185: GAF_2" amino acids 16 to 152 (137 residues), 60.2 bits, see alignment E=8.1e-20 PF01590: GAF" amino acids 17 to 152 (136 residues), 73.4 bits, see alignment E=8e-24 PF13492: GAF_3" amino acids 22 to 152 (131 residues), 41.5 bits, see alignment E=5.3e-14 PF05524: PEP-utilisers_N" amino acids 171 to 292 (122 residues), 79 bits, see alignment E=1e-25 TIGR01417: phosphoenolpyruvate-protein phosphotransferase" amino acids 172 to 730 (559 residues), 432 bits, see alignment E=1.6e-133 PF00391: PEP-utilizers" amino acids 320 to 390 (71 residues), 70.6 bits, see alignment E=2e-23 PF02896: PEP-utilizers_C" amino acids 418 to 705 (288 residues), 316.5 bits, see alignment E=4.9e-98

Best Hits

KEGG orthology group: K08484, phosphotransferase system, enzyme I, PtsP [EC: 2.7.3.9] (inferred from 100% identity to slo:Shew_1039)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.9

Use Curated BLAST to search for 2.7.3.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBR2 at UniProt or InterPro

Protein Sequence (743 amino acids)

>Shew_1039 phosphoenolpyruvate-protein phosphotransferase PtsP (RefSeq) (Shewanella loihica PV-4)
MLKTLRDITQAVAAADDLQSALSLLVRQTKSAMETQCCSIYILEEQELVLSATDGLDPRA
VGKVKMPMSQGLVGLVAEREEPVNLADAQQHPRFKLFTEVDEEDFRAFLAVPIIYQKLIL
GVLVVQQADARQFSEAEEAFLMTLAAQLAVAVREQRKKAEVKSAPDKCVYTGTSAASGVV
IAHAMVLGGEIPLEQQGRRTKQVDEELLALSQALDACRNTLSALSQRFDGENEKEVQSIF
SALQLLLDDTSLGGEYGREIQAGWTAISAVSRVSLRYIDHFQQMQDPYMQERATDIRDLG
QRVLRELIEPQKMQLELDVPVILVTKEATATMLAEFPQHKLVGIVTELGGVNSHAAILAR
AFGVPAVIGVEGILNAGIDGKQLILNANRGQVLISPTPTLIGEYRSLISAEKALQKRYAE
ELSKPAMTLDERRIHLYLNAGLLSSLASEIAEGADGVGLYRTEIPFMLQTRFPSEAEQVE
VYRQVLNAALGRPVVMRTLDVGGDKPLSYLPIIEENPFLGWRGIRLTLDHPELFLVQLRA
MLNASGGGEQLHILLPMVCCLDEIDQAIAYLEQAYLEVKQDVHPDLQRPKIGIMLEVPAL
LFQLEEVAKRVDFISVGSNDLTQYLLAVDRNNPRVSTLYDSYHPGILRALTQARLACREY
RLPISVCGELAGEPMGVLLLVAMGYTQLSMNQGSLAKINYLIRRVSYQDLSELLAQALSL
TNGFEVRELLTLYLKEKCLDEFL