Protein Info for Shew_0976 in Shewanella loihica PV-4

Annotation: binding-protein-dependent transport systems inner membrane component (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 70 to 90 (21 residues), see Phobius details amino acids 105 to 128 (24 residues), see Phobius details amino acids 140 to 160 (21 residues), see Phobius details amino acids 183 to 205 (23 residues), see Phobius details amino acids 241 to 263 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 79 to 271 (193 residues), 64.9 bits, see alignment E=4.2e-22

Best Hits

Swiss-Prot: 70% identical to POTI_ECOL6: Putrescine transport system permease protein PotI (potI) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K11074, putrescine transport system permease protein (inferred from 100% identity to slo:Shew_0976)

MetaCyc: 70% identical to putrescine ABC transporter membrane subunit PotI (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Putrescine transport system permease protein PotI (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBJ9 at UniProt or InterPro

Protein Sequence (275 amino acids)

>Shew_0976 binding-protein-dependent transport systems inner membrane component (RefSeq) (Shewanella loihica PV-4)
MSNRLRKLSFSTLMLWGGMFFLYAPMFILVFYSFNESKLVTVWGGFSAKWYGELFRDDQI
LDAVATSLKVAFFASTMAVILGTMAAFVMTRFARSWGKMTLSNMITAPLVMPEVITGLSL
LLLFVHMADLLGWPAERGMLTVWIAHSTFCAAYVAVVVSSRLRELDMSIEEAAQDLGATP
LKTFFHITVPMISPALIAGWLLSFSLSLDDLVIASFASGPGATTLPMVVFSSVRMGVSPK
INALATLIILIVSLIAFISWYLARRADKRSRMVSD