Protein Info for Shew_0700 in Shewanella loihica PV-4

Annotation: pirin domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 PF02678: Pirin" amino acids 28 to 118 (91 residues), 108.8 bits, see alignment E=1.4e-35 PF05726: Pirin_C" amino acids 179 to 282 (104 residues), 81 bits, see alignment E=7.5e-27

Best Hits

KEGG orthology group: K06911, (no description) (inferred from 100% identity to slo:Shew_0700)

Predicted SEED Role

"Pirin-like protein YhhW, possibly qercetin 2,3-dioxygenase activity"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QAS4 at UniProt or InterPro

Protein Sequence (286 amino acids)

>Shew_0700 pirin domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MKVISQFTARPAMDGDGVNIRRVADFMNTRFDPFLMLDEIKSDDANDYIGGFPPHPHRGI
ETFTYIRKGGFEHRDQLGNVKAIKAGDVQWMSTGSGVVHSEMPLADAQDGLHGFQIWLNM
PTKEKMRPAIYRDSTDEPLPETENDSGAKLRALAGSWQLTGAAPIDAPIQTLAGAGKIAD
LMLASNGSAQLDLHEREYVGLYLYQGEIVSQSAPQKTYSAGQYLIVDSQQLITLKAGEQG
AGALLFAGQPIREKIVHMGPFVMNTEQEIQQAIADYQAGRFGSIKA