Protein Info for Shew_0609 in Shewanella loihica PV-4

Annotation: two component LuxR family transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 PF00072: Response_reg" amino acids 13 to 120 (108 residues), 80.5 bits, see alignment E=1e-26 PF00196: GerE" amino acids 142 to 196 (55 residues), 76.4 bits, see alignment E=1e-25

Best Hits

Swiss-Prot: 40% identical to TMOT_PSEME: Response regulator protein TmoT (tmoT) from Pseudomonas mendocina

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0609)

Predicted SEED Role

"Tetrathionate reductase two-component response regulator" in subsystem Tetrathionate respiration

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QAI3 at UniProt or InterPro

Protein Sequence (199 amino acids)

>Shew_0609 two component LuxR family transcriptional regulator (RefSeq) (Shewanella loihica PV-4)
MPQATPQPMPLYLVDDDEAVLDSLSFMLRQFGYEMTTFVSGLRFLEEVDLSRPGCVILDS
RMPAISGQALQQELLTKQSPLGIIFLTGHGDLPMAVNAFRQGACDFFQKPVSGQALAAAI
DKSMLHSQKAFEALQLSHNLATLSDREHQVLELLIQGKTNKQLSEALFLSLRTIEVHRSN
VMKKLKVHNLAELAKYSQI