Protein Info for Shew_0498 in Shewanella loihica PV-4

Annotation: flavoprotein oxygenase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 209 PF01613: Flavin_Reduct" amino acids 28 to 170 (143 residues), 74.5 bits, see alignment E=5.2e-25

Best Hits

Swiss-Prot: 33% identical to Y2278_BACHD: Uncharacterized protein BH2278 (BH2278) from Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0498)

Predicted SEED Role

"Flavin reductase-like, FMN-binding domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QA72 at UniProt or InterPro

Protein Sequence (209 amino acids)

>Shew_0498 flavoprotein oxygenase (RefSeq) (Shewanella loihica PV-4)
MDTQARYYYEPSKGHGLAHDPLNAIVGPRPIGWIASRSPEGHRNLAPYSFFNCFNYHPPI
IGFASVGYKDSLANILATGEFVWNLATRPLAEKMNLTSAALPAGSDEFDFAGLTPVAGSV
VGVDRVAESPVNFECRLTQSLQLQSAAGDKIETWLVLGEVVAVHIDPSLIEDGSYQTAKA
KPILRAGGPSAYYGISEALRFDMQRPQVP