Protein Info for Shew_0490 in Shewanella loihica PV-4

Annotation: peptidase S9 prolyl oligopeptidase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 675 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF07676: PD40" amino acids 89 to 114 (26 residues), 22.5 bits, see alignment (E = 2.6e-08) amino acids 272 to 292 (21 residues), 16.7 bits, see alignment (E = 1.8e-06) PF00326: Peptidase_S9" amino acids 468 to 668 (201 residues), 204.3 bits, see alignment E=5.3e-64

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0490)

Predicted SEED Role

"Peptidase S9, prolyl oligopeptidase active site region:Peptidase S9, prolyl oligopeptidase active site region precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QA64 at UniProt or InterPro

Protein Sequence (675 amino acids)

>Shew_0490 peptidase S9 prolyl oligopeptidase (RefSeq) (Shewanella loihica PV-4)
MKKIAILLLCILMPVTTVFAQTGKPLSVEVLWQLSRIGNPSISPNGDYIIAPVTEYDVPE
DKGNTQLWLFSQDGKQQRALTAKGMRVSEPVFSPDSKTLAFISKRDKDEAGQIYLLPMDG
PGEAQRLTDVPSGVYGLKWVGEHLYFISSVYPGKNWKEIGEQLKADKDNKVSAHQWNALP
YSSFDHWIDEGRQAHVFRIAAKGGEVEAITQPLNIELPRSSQGAGSYDISPDEAWIAFNA
NGSDNQVNPKLDLFLAAIGSGKAENITPDNLAPDASPQFSPNGKTLAFTRQHIQGFYADT
AKLMLFDLKKRSTKMLAKEWDRSVARFVWTPDSKGFYAAIDDAATRRLYHIDAKSGKVKA
ITKATNFGQPAIANNGTLVATNDSFLYPARLVKVNGKNGKTSRLDSFNDEILADVDLGSY
ESVTYKGYNDQEIQMWVHYPPGFDRSKKYPLMMLVHGGPHNAISDGFHYRWNAQTFASWG
YVTAWPNFHGSNSFGQAFADSINPDWKNKSLEDVLKAADWFKQQSWIDDKRMVAGGASYG
GYLTSIILGQKHPFNALLIHAAVYNMYSQMAADFSVHSPRFGNYWDNPEIYQSISPHYGA
GNFNTPTLVIHGQLDYRVPVGQGFELFRTLQTRGVESRMIYFPDENHWIMKPNNSIYWYH
QVKDWMTRFAEPGGK