Protein Info for Shew_0371 in Shewanella loihica PV-4

Annotation: AraC family transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 PF00165: HTH_AraC" amino acids 20 to 60 (41 residues), 33.6 bits, see alignment 6.4e-12 amino acids 76 to 111 (36 residues), 30.9 bits, see alignment 4.6e-11 PF12833: HTH_18" amino acids 33 to 111 (79 residues), 74.1 bits, see alignment E=1.9e-24 PF06445: GyrI-like" amino acids 135 to 288 (154 residues), 122.1 bits, see alignment E=5.2e-39 PF14526: Cass2" amino acids 138 to 273 (136 residues), 41.7 bits, see alignment E=2.8e-14

Best Hits

KEGG orthology group: K13652, AraC family transcriptional regulator (inferred from 100% identity to slo:Shew_0371)

Predicted SEED Role

"Uncharacterized protein ygiV"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9U5 at UniProt or InterPro

Protein Sequence (288 amino acids)

>Shew_0371 AraC family transcriptional regulator (RefSeq) (Shewanella loihica PV-4)
MNRAAHQAYSQRIQTVCDYIAKHLEQPLTLEQLSQKAHFSKYHFHRQFQVYTGITLGKYI
SLLRLKRASYRLVFHPELKITDIALDAGFENGESFSRAFKQVFAQTPTQFRLTPKWEQWS
QQYAKVNYTRRETVQIKLTQRDDIKVAVLEHQGSPAALNDSIQQFINWRKQSGESPVASS
LTLGVPFNDPNTVAPEAFRFDICGSVTAEVKANDFGVITKTIPGGRCAVIRHLGPHDQMD
DKIYQFYRDWLPQSGEELRDFPLYFEYHNFFPEVAEHELVTKIYFSLK