Protein Info for Shew_0331 in Shewanella loihica PV-4

Name: prmA
Annotation: ribosomal protein L11 methyltransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 TIGR00406: ribosomal protein L11 methyltransferase" amino acids 3 to 285 (283 residues), 332.3 bits, see alignment E=1.4e-103 PF06325: PrmA" amino acids 3 to 293 (291 residues), 354.7 bits, see alignment E=1.4e-109 PF05175: MTS" amino acids 144 to 210 (67 residues), 38.8 bits, see alignment E=2.4e-13 PF13847: Methyltransf_31" amino acids 159 to 207 (49 residues), 28.7 bits, see alignment 2.9e-10 PF13649: Methyltransf_25" amino acids 163 to 206 (44 residues), 29.1 bits, see alignment 4e-10 PF08241: Methyltransf_11" amino acids 164 to 216 (53 residues), 27.6 bits, see alignment 1.1e-09

Best Hits

Swiss-Prot: 100% identical to PRMA_SHELP: Ribosomal protein L11 methyltransferase (prmA) from Shewanella loihica (strain ATCC BAA-1088 / PV-4)

KEGG orthology group: K02687, ribosomal protein L11 methyltransferase [EC: 2.1.1.-] (inferred from 100% identity to slo:Shew_0331)

MetaCyc: 66% identical to ribosomal protein L11 methyltransferase (Escherichia coli K-12 substr. MG1655)
RXN0-5419

Predicted SEED Role

"Ribosomal protein L11 methyltransferase (EC 2.1.1.-)" in subsystem Heat shock dnaK gene cluster extended or Ribosome biogenesis bacterial (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9Q5 at UniProt or InterPro

Protein Sequence (293 amino acids)

>Shew_0331 ribosomal protein L11 methyltransferase (RefSeq) (Shewanella loihica PV-4)
MAWIQLKIDTDNQHAEQLSDMLMELGSLSITYEDGKDTPIYEPNLGETPLWSHTVITALF
EADYDLAPVVEMLKLQPYLGADFSHKIEQVEDKDWEREWMDNFHPIQFGRRLWICPSWRE
VPDPEAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLQGKEAIDFGCGSGILAVAALKLG
AAKVTGIDIDYQAIDASKANAERNQVADKLDLYLPEDQPADLKAEVLVANILAGPLRELA
PLIAEKVQPGGLLALSGLLKEQADEISQHYAQWFDMDAPVHKEDWSRLTGRRK