Protein Info for Shew_0327 in Shewanella loihica PV-4

Annotation: HupE/UreJ protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 35 to 52 (18 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 86 to 104 (19 residues), see Phobius details amino acids 110 to 127 (18 residues), see Phobius details amino acids 139 to 162 (24 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details PF04955: HupE_UreJ" amino acids 9 to 186 (178 residues), 190.5 bits, see alignment E=9.4e-61

Best Hits

KEGG orthology group: K03192, urease accessory protein (inferred from 100% identity to slo:Shew_0327)

Predicted SEED Role

"Nickel-binding accessory protein UreJ-HupE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9Q1 at UniProt or InterPro

Protein Sequence (191 amino acids)

>Shew_0327 HupE/UreJ protein (RefSeq) (Shewanella loihica PV-4)
MRTRLLPLLLLAWTTPVFAHGITHGAGFMTGFNHPVLGFDHLLAMLSVGLLSTQLGGRAI
WTVPLAFMAFMLVGGILGLYGVALPWVELGIALSVLLLGLAIALGRHIPLLLAMGFVGLF
AIFHGHAHGAEMPALASPVLYALGFLTGTAVIHLLGVALGIIMQQLSHKLPLLRLSGGVI
ALVGGYLIVGA