Protein Info for Shew_0257 in Shewanella loihica PV-4

Annotation: peptidase S9 prolyl oligopeptidase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 692 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF07676: PD40" amino acids 86 to 110 (25 residues), 19.1 bits, see alignment (E = 3.2e-07) PF00326: Peptidase_S9" amino acids 483 to 681 (199 residues), 151.9 bits, see alignment E=5.6e-48 PF01738: DLH" amino acids 509 to 668 (160 residues), 40 bits, see alignment E=1e-13 PF03959: FSH1" amino acids 521 to 650 (130 residues), 23.9 bits, see alignment E=9e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0257)

Predicted SEED Role

"Prolyl oligopeptidase family (Peptidase_S9) (EC 3.4.21.26)" (EC 3.4.21.26)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.26

Use Curated BLAST to search for 3.4.21.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3Q9I1 at UniProt or InterPro

Protein Sequence (692 amino acids)

>Shew_0257 peptidase S9 prolyl oligopeptidase (RefSeq) (Shewanella loihica PV-4)
MGRGYQLTALAAICAGAMGLSSGVLAAERTHQITTDDFFTIGNMGNVQLSPDGKHALWLE
SRWDKELDKAQKDLWLIDTKSRKTNRLTFTNESESSPQWSPDGSAIYYLVKQSREDNKAP
YNGKAQVFRINLGSTEAVPVTKEAEGVKQFQLSQDGKSLYFLTNKTTTDKDIWAKVRAKH
GAPKYGHGKVTTNPLYKLDLDHYQQSLVLDDDKVVWNFSVNQDASQIARITTQDNELVNL
EGWSNIEVFNTQSQQNKVLEDSAWREQAPSPYGWLLGLAWHEDNQRLAFRIDFDGHPGKL
FVVKPKDDKAKLIQVKTEGDVTFNSSDIHWRPGSDELCYRGYDHARVKLFCSEIDNQGQG
DTRTVLAGDLVMGSYSFTHNGKKLAFSHNGLDHFSDLFIADAASKKAKYKRLTNINPQVD
SWILPEISIVKWTAPDGSQVEGILDLPAGYKKSDGPLPLIVQIHGGPTSATPYALQHRSY
GRSTFTANGWALLSPNYRGSTGYGDKFLTDLVGQEHEIEVADIMAGVDHLIKQGIADGDK
MAVMGWSNGGYLTNALISTTNRFKAASSGAGVFDQRLQWMLEDTPGHVINFMQGLPWEKP
EAYTHGSSLTHADKIKTPTLIHIGENDQRVPLGHAQGLYRALKHYLNVPVELVVYPGEGH
GLSKYQHRQAKMDWDKLWFEHYVLGKQMDEAK