Protein Info for Dshi_3688 in Dinoroseobacter shibae DFL-12

Annotation: BioY protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 transmembrane" amino acids 17 to 36 (20 residues), see Phobius details amino acids 41 to 62 (22 residues), see Phobius details amino acids 68 to 88 (21 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 125 to 149 (25 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details PF02632: BioY" amino acids 39 to 182 (144 residues), 109.7 bits, see alignment E=6.1e-36

Best Hits

KEGG orthology group: K03523, putative biotin biosynthesis protein BioY (inferred from 100% identity to dsh:Dshi_3688)

Predicted SEED Role

"Substrate-specific component BioY of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LT54 at UniProt or InterPro

Protein Sequence (190 amino acids)

>Dshi_3688 BioY protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MGTGIGQRCPVRAGRKGALILVGVAVILLSISSYIEIPMVPVPITAQTFMVLTVGAVLGP
LLGTIGTVIWLLCGAVGLPVLAGGASGLGHFMGPTAGFLFAFPIAALTAGVLVSKRQGAG
VAYRAWWVFLAGIAGHIICLGLGVLWLSTLIGIGAALENGFFPFILGGILKSTAVAAVVI
GIELQSGKTS