Protein Info for Dshi_3447 in Dinoroseobacter shibae DFL-12

Annotation: protein-export protein SecB (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 172 PF02556: SecB" amino acids 19 to 159 (141 residues), 172.8 bits, see alignment E=2e-55 TIGR00809: protein-export chaperone SecB" amino acids 20 to 156 (137 residues), 117.5 bits, see alignment E=2.3e-38

Best Hits

Swiss-Prot: 100% identical to SECB_DINSH: Protein-export protein SecB (secB) from Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)

KEGG orthology group: K03071, preprotein translocase subunit SecB (inferred from 100% identity to dsh:Dshi_3447)

Predicted SEED Role

"Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LPB5 at UniProt or InterPro

Protein Sequence (172 amino acids)

>Dshi_3447 protein-export protein SecB (RefSeq) (Dinoroseobacter shibae DFL-12)
MADETTNGAAAPADQQQQPVMPTLKIMAQFIRDMSFENIAAQKGVQGEGQPDIQVQVNLD
AKKRTVEKQFEVAIKLNINAKTKESGDMIFGLELDYAGIFFIDNVPDEQMHPFLLIECPR
MIFPFVRRIVSDVTRDGGFPPLNLDQIDFVALYRQEIARRAAAQQAAPSAEV