Protein Info for Dshi_3421 in Dinoroseobacter shibae DFL-12
Annotation: peptidase S8 and S53 subtilisin kexin sedolisin (RefSeq)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3421)Predicted SEED Role
"Extracellular protease"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A8LP89 at UniProt or InterPro
Protein Sequence (496 amino acids)
>Dshi_3421 peptidase S8 and S53 subtilisin kexin sedolisin (RefSeq) (Dinoroseobacter shibae DFL-12) MKPFKALLALVLVGLLWSSPSQVAAQTAPALPECVNPGDLITIPRVRNPPPIRATLFLDF GDFRVRVLIRNVTASSFSFRMPRLQRTPRNGEFELVVRLLLGVERTLRTGRICQGRLLEE ALDRIPDVPIRPATGNEVAAPSGGPEYVLAGTDQEIARARVVLRGARAQILRSQRLGSLG QSLLFVDLAGALTEAQARALLAREGIRSAIGTHTVYSLSQSSGGRAGLRLFATALVRPDP GRNCTLTRPVRVGLIDGPLDLRTPSLTNVRVTSLSVLRPRERPGSTAHGTGIAALIAGQA TTQGPAGLAPGAELLSVVAFARAGGRDLARLENIALGLDWLVERGADVVNMSLAGPPNEA LAALVEIADQQGLIMVAAAGNRGEPSLGYPAADPRVLAITAIDADKRIYRRASFGAGMDF SAPGVDIAVPDRRGWSYRSGTSYAAAVATGLVAQKLAQQRLTTDQLRASFRRSAEDLGPS GYDPRFGWGLMRGDPC