Protein Info for Dshi_3207 in Dinoroseobacter shibae DFL-12

Annotation: protein of unknown function DUF989 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 17 to 36 (20 residues), see Phobius details amino acids 84 to 104 (21 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details amino acids 229 to 246 (18 residues), see Phobius details amino acids 252 to 271 (20 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details PF06181: Urate_ox_N" amino acids 6 to 298 (293 residues), 435.9 bits, see alignment E=4e-135

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_3207)

MetaCyc: 61% identical to membrane-bound urate hydroxylase (Agrobacterium fabrum C58)
1.14.99.-

Predicted SEED Role

"FIG137887: membrane protein related to purine degradation"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LM31 at UniProt or InterPro

Protein Sequence (410 amino acids)

>Dshi_3207 protein of unknown function DUF989 (RefSeq) (Dinoroseobacter shibae DFL-12)
MYDLAILWDWIAFSVRWLHVITAMAWIGASFYFIALDLMLKPNQALPDGAYGEEWEVHGG
GFYHTVKYLVAPARMPEHLTWHKWQSYATWLSGAALLAIIYWVGGELYLLDPTKADLALW
QGIAISAGSLTIGWLLYDAMCKSRLADSPTLLMLLLFVILVIMSWGYNQIFTGRAALLHL
GAFTATIMTANVFFQIMPNQRIVVEDLKAGRQPDPKYGKIAKVRSTHNNYLTLPVVFLML
SNHYPLAFATEFAWIIASLIFLTGVTIRHYFNTMHKTGKGPIWTWGVTVGLMIAIAWLST
FSSGNTFEDAEARALTPYEQQYASAAGFDAAYEAVLGNCSMCHAREPLWGNMQWAPKDVH
LETPGDVARQASAIYLQAGVSHAMPPPSAVQMDDEARQAIVAWVREVRSQ