Protein Info for Dshi_3185 in Dinoroseobacter shibae DFL-12

Annotation: ATPase associated with various cellular activities AAA_5 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 PF07728: AAA_5" amino acids 35 to 169 (135 residues), 138.1 bits, see alignment E=3.1e-44 PF08406: CbbQ_C" amino acids 182 to 266 (85 residues), 107.9 bits, see alignment E=3.6e-35

Best Hits

Swiss-Prot: 82% identical to NORQ_PARDP: Protein NorQ (norQ) from Paracoccus denitrificans (strain Pd 1222)

KEGG orthology group: K04748, nitric oxide reductase NorQ protein (inferred from 100% identity to dsh:Dshi_3185)

Predicted SEED Role

"Nitric oxide reductase activation protein NorQ" in subsystem Denitrification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LM09 at UniProt or InterPro

Protein Sequence (268 amino acids)

>Dshi_3185 ATPase associated with various cellular activities AAA_5 (RefSeq) (Dinoroseobacter shibae DFL-12)
MDGSHMNGNGASAPFYLAQGDECSLFEAAYDNNLPLLLKGPTGCGKTRFVAHMAARLGRP
LYTVACHDDLTAADLVGRYLLKGGETVWVDGPLTRAVREGAICYLDEVVEARKDVTVVLH
PLTDDRRILPIDRTGEELEATPGFMLVASYNPGYQNILKTLKPSTRQRFLSLEFGFPAPA
HEVEIVASESGLSVERVKPLVRLAGKLRDLKGQDIEEGVSTRLIVYAATLIAKGMPVERA
IRTAMIEPLTDEEDVKRGLTDLVTAVFG