Protein Info for Dshi_2779 in Dinoroseobacter shibae DFL-12

Annotation: protein of unknown function UPF0005 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 240 transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 55 to 80 (26 residues), see Phobius details amino acids 92 to 111 (20 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 148 to 165 (18 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details amino acids 214 to 236 (23 residues), see Phobius details PF01027: Bax1-I" amino acids 24 to 236 (213 residues), 215 bits, see alignment E=5.3e-68

Best Hits

Swiss-Prot: 41% identical to Y147_RICPR: Uncharacterized protein RP147 (RP147) from Rickettsia prowazekii (strain Madrid E)

KEGG orthology group: K06890, (no description) (inferred from 100% identity to dsh:Dshi_2779)

Predicted SEED Role

"FIG005935: membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LJ17 at UniProt or InterPro

Protein Sequence (240 amino acids)

>Dshi_2779 protein of unknown function UPF0005 (RefSeq) (Dinoroseobacter shibae DFL-12)
MAQYDTIRTAGAGVRTAQIDEGLRAHFNKVYGLMSVAMVLTGAVAWAVGTNEAMLAAIFA
TPMKWVVMFAPLIMVFAFSAMINKMSAAAAQVFFYTFAAAMGLSISFIFAVYTGVSIAST
FLVTAIAFASLSLFGYTTKKDLSSWGRFLFMGVIGLIVASIINLFLGSPAIAFAVSSLGV
LIFAALTAYDTQRIKTEYIEHAQYGDQEWLNKSAIMGALSLYINFINLFMFLLQFLGNRE