Protein Info for Dshi_2120 in Dinoroseobacter shibae DFL-12

Annotation: ABC transporter related (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 PF00005: ABC_tran" amino acids 31 to 172 (142 residues), 134.3 bits, see alignment E=4.7e-43 PF08402: TOBE_2" amino acids 296 to 368 (73 residues), 40.7 bits, see alignment E=2.2e-14

Best Hits

Swiss-Prot: 43% identical to POTA_THEFY: Spermidine/putrescine import ATP-binding protein PotA (potA) from Thermobifida fusca (strain YX)

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 100% identity to dsh:Dshi_2120)

Predicted SEED Role

"Maltose/maltodextrin transport ATP-binding protein MalK (EC 3.6.3.19)" in subsystem Maltose and Maltodextrin Utilization (EC 3.6.3.19)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.19

Use Curated BLAST to search for 3.6.3.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LQI9 at UniProt or InterPro

Protein Sequence (376 amino acids)

>Dshi_2120 ABC transporter related (RefSeq) (Dinoroseobacter shibae DFL-12)
MKANAQMDQSSEPIVKFDNVVKRFGSFTAVKKADFEIGRGEFLAIMGSSGCGKTTTLRML
AGLEDPTEGAIYLDGEQVNGKATWDRDTPMVWQSLALFPFLTVQENVEFALKMRGIGKEE
RRQRADKWLDKMQITEFADRNINQLSGGQKQRVALARALVTEPKILLLDEPLSALDAHLK
VRMQSVLSNLQKDLGITFVYVTHSMSEAFSMADRVVIMSRGQIEQIGTPEEIYREPHNRF
VAEFLGSANIFDGVVEGPAEDGGWRVSYEGGETVLDKSELAEARKGQAVTFIVSAENMQL
SLPDSGQPGIAASVAGEEFIGGTAMVFLETATGQELKVQKTHEELSQLDLHAGSRIIVHW
APDSCHVLPGETGARN