Protein Info for Dshi_2050 in Dinoroseobacter shibae DFL-12

Annotation: protein of unknown function DUF140 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 transmembrane" amino acids 136 to 153 (18 residues), see Phobius details amino acids 174 to 196 (23 residues), see Phobius details amino acids 222 to 243 (22 residues), see Phobius details amino acids 264 to 284 (21 residues), see Phobius details amino acids 290 to 308 (19 residues), see Phobius details amino acids 320 to 344 (25 residues), see Phobius details amino acids 358 to 380 (23 residues), see Phobius details PF13466: STAS_2" amino acids 35 to 101 (67 residues), 50.3 bits, see alignment E=2.2e-17 TIGR00056: ABC transport permease subunit" amino acids 154 to 383 (230 residues), 232.4 bits, see alignment E=3.6e-73 PF02405: MlaE" amino acids 168 to 377 (210 residues), 237.5 bits, see alignment E=1.2e-74

Best Hits

KEGG orthology group: K02066, putative ABC transport system permease protein (inferred from 100% identity to dsh:Dshi_2050)

Predicted SEED Role

"ABC-type transport system involved in resistance to organic solvents, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LPT3 at UniProt or InterPro

Protein Sequence (384 amino acids)

>Dshi_2050 protein of unknown function DUF140 (RefSeq) (Dinoroseobacter shibae DFL-12)
MAATDAAEYAEGRGVDARPAPDLRLSQDEAGVAGALSGDLTIYGVADLQRQLAARPAGSL
TLDLSGIGRIDTAGAWLLAELARGEGVRLVGAPDKVARLIANVAKAEPEHPERTETPPTL
TDRLERLGRQVVEGTKFLGGLTGMLGLVLARFGRALRHPREFRMTALVHHCEEVGLRAVP
IVALMAFLIGIVLAFQGASQLRQFGAEVFVVDLISISILRELGILLTAIIVAGRTASSFT
AAIGSMKMREEIDAMRTLGLDPAMLLFLPRVLALLIMLPILGLIANLSGLLGGALMSWIE
LGISPAMFQTRLIEGTDINHAVVGLVKAPFFAILIGVVGCHAGMQVEGNAESLGRMTSGA
VVTAIFAVIVTDAAFSIFFAQMGI