Protein Info for Dshi_1545 in Dinoroseobacter shibae DFL-12

Annotation: extracellular solute-binding protein family 5 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 606 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF00496: SBP_bac_5" amino acids 104 to 504 (401 residues), 217.9 bits, see alignment E=1.2e-68

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 100% identity to dsh:Dshi_1545)

Predicted SEED Role

"ABC transporter, periplasmic substrate-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LK88 at UniProt or InterPro

Protein Sequence (606 amino acids)

>Dshi_1545 extracellular solute-binding protein family 5 (RefSeq) (Dinoroseobacter shibae DFL-12)
MKQLRRAIRIGHAALIAGFLAVPGALAAPSHGIAMYGDPALPPDFVSLPYANPDAPKGGR
IVLGEVGGFDSLNPHILKGRVPWQLRFLAHESLMARNYDEPFALYGLLAESVEVDPDGLW
VAFTLRPEARFSDGSPVTVEDVLWSFETLGTVGHPRYLGAWAQVQSAEATGPRSLRITFT
EPNRELALIMGMRPILKKAQWEGKDFAESGLDEAPISSAPYVIADFEPGRFVTLRRNPDY
WAADLPIRRGVHNLDEIRMEFFGDAGVMFEAFKAGILTSIRETNTAKWNRDYDFPAMQAG
EVVKSVIPHERPSGITGFAMNTRRADFADWRVRDALIHAFNFELINRTLNGAEVPRITSY
FSNSVLAMQDGPATGRVAELLAPYADTLPPGALEGYTLPVSDGSEANRRNIRAALRLMDE
AGYTIEEGVMTRPDGTPFTFEILLSQGSSEVQSMINIYAKSLERLGVSVDITTVDSAQYR
ERTDAYDFDMTYYTRGLSLSPGNEQRLYWGSEGVDIPGSRNWPGIDSAAVDGLIDAMLSA
KSQEDYIATVRALDRVLTAGRYVIPIWFNPVSRIAHAADLTYPEALPAYGDWISFHPDVW
WSKSAE