Protein Info for Dshi_1168 in Dinoroseobacter shibae DFL-12

Annotation: aminotransferase class I and II (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00155: Aminotran_1_2
  • amino acids 31 to 370 (340 residues), 187.5 bits, E=2.2e-59

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_1168)

Predicted SEED Role

"Valine--pyruvate aminotransferase (EC 2.6.1.66)" in subsystem Alanine biosynthesis or Branched-Chain Amino Acid Biosynthesis or Pyruvate Alanine Serine Interconversions (EC 2.6.1.66)

MetaCyc Pathways

• L-alanine biosynthesis I (2/2 steps found)
• superpathway of L-alanine biosynthesis (3/4 steps found)

KEGG Metabolic Maps

• Valine, leucine and isoleucine biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.66

Sequence Analysis Tools

See A8LHW3 at UniProt or InterPro

Protein Sequence (391 amino acids)

>Dshi_1168 aminotransferase class I and II (RefSeq) (Dinoroseobacter shibae DFL-12)
MQNSSRSEVDPFIVMDVMEAARRAEAAGRHIIHMEVGQPGTAAPLPARRAVAAQLDQDAM
GYTVALGLPELRRAIAGLYARWYGVDLDPARVVVTSGSSAAFLLAFTTYFDAGARVGVAE
PGYPSYRQILKALSLAPVGLPTQPETGHRMTAEALAQADIAGAIIASPNNPTGTMLDRDG
LGALIAACRDRDRVFISDEIYHGLHYGDRAVSALEISDDVCVINSFSKYFSMTGWRIGWL
VVPEAQVRVVERLAQNMFICAPHVAQIAALGALGDAARPELEANRAVYAANRQLVIDGLR
AAGLDAFAPPDGAFYVYVDTGALSSDSRTLAADILEKAGVAVTPGLDFDPVRGHGTLRLS
YARATEDIAEGMTRLTNYFAAAGPNPLLTGS