Protein Info for Dshi_1125 in Dinoroseobacter shibae DFL-12

Annotation: type II secretion system protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details amino acids 87 to 111 (25 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 262 to 282 (21 residues), see Phobius details amino acids 294 to 314 (21 residues), see Phobius details PF19360: TadB_TadC_N" amino acids 1 to 143 (143 residues), 229.8 bits, see alignment E=9.6e-73 PF00482: T2SSF" amino acids 155 to 277 (123 residues), 56.7 bits, see alignment E=2.4e-19

Best Hits

KEGG orthology group: K12510, tight adherence protein B (inferred from 100% identity to dsh:Dshi_1125)

Predicted SEED Role

"Flp pilus assembly protein TadB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LHS0 at UniProt or InterPro

Protein Sequence (322 amino acids)

>Dshi_1125 type II secretion system protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MTISIEPLIYIGIFVGVLFLVEGIYLVAFGKSISLNSKVNRRLDMLDKGATRDAVLDQLR
KEMSQHKTTSILPLYAMLADKAKKGNIAFSPAALIMIMVLLMGVSFVGLTLGTQASLAVR
VVASVAIGIGAVYMWVNKKAKQRLAMIEEQLPDAVELMVRSLRVGHPFSSAINIVAKEVA
DPLGTEFGMIADEAAYGRDVTEALKELAERMDMQDLRFLAVAVSIQSQSGGNLAEILDGL
AKVIRARFKLFRRVKAITAEAKWSGMFLSGFPFLALVGINLMEPDYYADVKDTPAFIPAC
VVVAVFLTINIIFMKMMVNIKV