Protein Info for Dshi_0732 in Dinoroseobacter shibae DFL-12

Annotation: cation antiporter (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 117 transmembrane" amino acids 7 to 30 (24 residues), see Phobius details PF01899: MNHE" amino acids 7 to 109 (103 residues), 108.1 bits, see alignment E=1.7e-35

Best Hits

KEGG orthology group: K05569, multicomponent Na+:H+ antiporter subunit E (inferred from 100% identity to dsh:Dshi_0732)

Predicted SEED Role

"Na(+) H(+) antiporter subunit E" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LQT4 at UniProt or InterPro

Protein Sequence (117 amino acids)

>Dshi_0732 cation antiporter (RefSeq) (Dinoroseobacter shibae DFL-12)
MKLVLRIYYSINLFVYFLYELLVSSVQVAWDVLTPEMKARPILVVVPLDAKTDLELMLTA
NIISLTPGTLSIDLSADRTELLVHSMFGAKDPEGEIAAMKHGIERRVLRATRGVHLA