Protein Info for Dshi_0621 in Dinoroseobacter shibae DFL-12

Annotation: beta-Ig-H3/fasciclin (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02469: Fasciclin
  • amino acids 40 to 162 (123 residues), 140.4 bits, E=1.7e-45

Best Hits

Swiss-Prot: 52% identical to Y1735_SYNY3: Uncharacterized protein sll1735 (sll1735) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_0621)

MetaCyc: 44% identical to CO2 hydration protein CupS (Synechococcus elongatus PCC 7942 = FACHB-805)
Carbonate dehydratase. [EC: 4.2.1.1]

Predicted SEED Role

"Sensory subunit of low CO2-induced protein complex, putative" in subsystem CO2 uptake, carboxysome

MetaCyc Pathways

• cyanate degradation (2/3 steps found)
• 3-hydroxypropanoate cycle (9/13 steps found)
• CO₂ fixation into oxaloacetate (anaplerotic) (1/2 steps found)
• superpathway of the 3-hydroxypropanoate cycle (12/18 steps found)
• C4 photosynthetic carbon assimilation cycle, NADP-ME type (4/7 steps found)
• glyoxylate assimilation (8/13 steps found)
• 3-hydroxypropanoate/4-hydroxybutanate cycle (11/18 steps found)
• C4 photosynthetic carbon assimilation cycle, NAD-ME type (5/11 steps found)
• C4 photosynthetic carbon assimilation cycle, PEPCK type (7/14 steps found)
• gluconeogenesis II (Methanobacterium thermoautotrophicum) (7/18 steps found)
• Methanobacterium thermoautotrophicum biosynthetic metabolism (19/56 steps found)

KEGG Metabolic Maps

• Nitrogen metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.1

Use Curated BLAST to search for 4.2.1.1

Sequence Analysis Tools

See A8LPP4 at UniProt or InterPro

Protein Sequence (162 amino acids)

>Dshi_0621 beta-Ig-H3/fasciclin (RefSeq) (Dinoroseobacter shibae DFL-12)
MNRRFALKTAAAFGLVGLVAACDPMAGGNDIVDIASSNADFSTLVAAVSAAGLVDTLKGD
GPFTVFAPTNDAFAALPAGTVESLLEPENRDQLVAILTYHVIPGAVTSDQLAGATLDVAT
VQGGTVKVDGTDGVMVNDATVTTADITASNGVIHVIDKVLLP