Protein Info for Dshi_0512 in Dinoroseobacter shibae DFL-12

Annotation: beta-lactamase domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 PF00753: Lactamase_B" amino acids 98 to 189 (92 residues), 45.3 bits, see alignment E=9.9e-16 PF12706: Lactamase_B_2" amino acids 135 to 187 (53 residues), 27.9 bits, see alignment E=1.7e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_0512)

Predicted SEED Role

"alkyl sulfatase (EC 3.1.6.-)" (EC 3.1.6.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.6.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LNV0 at UniProt or InterPro

Protein Sequence (225 amino acids)

>Dshi_0512 beta-lactamase domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MPSQFTIDILNEAREALPFDDTQDFDELARGLIAAPETLQIEAEAGGFTWELERFNFLKE
GENFDSIHPSLERQARLTTQFGLYEVMEGIYQVSGYDLSNPTLIQTDSGWIAYDVLLSKE
TAEATMELVNQELGKRPIVAVIYSHSHADHFGGVRALVDDAAIEAGEVEIIAPEGFIEHA
VSENVYAGNAMTRRRFYQYASLLPASPFGYVTKASARLPPAAPRA